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PHARMACEUTICAL AND BIOPHARMACEUTICAL
WORKFLOW SOLUTIONS:

KARL FISCHER TITRATION
Date: Thursday, September 03, 2020
Time: 09:00 AM Central European Summer Time (GMT+02:00)
Location: Location of the webinar
Duration: 1 hour
On-demand webinar recording

Karl Fischer titration (KFT) is the preferred technique for water determination due to its superior accuracy, increased speed and selectivity, and practical advantages over other methods.

Today, however, the lack of skilled chemists with experience using the KFT technique can undermine its effectiveness and the quality of results. This situation can have serious consequences in the biopharmaceutical field where water content impacts drug stability, crystal structure, powder flow, dissolution rate, and polymer film permeability in solid dosage forms. It can also lead to growth of microorganisms if unchecked. Errors in analysis often result in costly production stoppages and health risks.

Join this webinar and learn how Hydranal™, Honeywell’s Karl Fischer titration product line, focuses on optimizing the water determination workflow on following steps:

  1. Instrument and reagent setup in volumetry and coulometry with suitable drying agents
  2. System calibration with reference materials and certified reference materials (CRMs)
  3. Sample preparation, analysis and method adaptation with special media, solublizers and buffers
  4. Results validation with water standards

Speaker

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Agnieszka Kossakowska
HYDRANAL Marketing Specialist
Honeywell Research Chemicals
Agnieszka joined Honeywell in March 2016 as a marketing specialist providing technical support and on-site seminars for Honeywell’s Hydranal™ reagents for Karl Fischer titration. She has more than 10 years of experience in analytical chemistry and conducts trainings worldwide.
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